Description

Acth (4-10), Phe(7)- CAS NO 39877-09-3 is a synthetic peptide fragment of the adrenocorticotropic hormone (ACTH), specifically the sequence from amino acids 4 to 10 with a phenylalanine substitution at position 7. This compound is of significant interest in biochemical and pharmacological research due to its role in studying melanocortin receptor interactions and neuropeptide functions. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on neuroscience, endocrinology, and peptide-based drug discovery.

Application

• Neuroscience Research: Investigation of melanocortin system function, neuroprotection, and neuroinflammatory pathways.
• Endocrinology Studies: Research into ACTH fragment activity, steroidogenesis, and adrenal gland function.
• Pharmacological Screening: Used as a reference standard or active agent in high-throughput screening for melanocortin receptor (MCR) agonists/antagonists.
• Academic Research: Fundamental studies on peptide structure-activity relationships (SAR) and signal transduction mechanisms.
• Pharmaceutical R&D: Early-stage development of novel therapeutics targeting conditions related to stress, inflammation, and metabolic disorders.

Basic Information

Product Name	Acth (4-10), Phe(7)- CAS NO 39877-09-3
CAS No.	39877-09-3
Molecular Formula	C44H62N12O10S
Molecular Weight	951.1 g/mol
Synonyms	ACTH (4-10), Phe(7)-; H-Met-Glu-His-Phe-Arg-Trp-Gly-OH (Phe7 substitution); Adrenocorticotropic Hormone Fragment 4-10 (Phe7); Melanocyte-Stimulating Hormone Release-Inhibiting Factor (Fragment); [Phe7]-ACTH (4-10); ACTH (4-10) analog; [Phe7]-Corticotropin (4-10); Research Peptide 39877-09-3
EINECS	Contact for details

Quality Control

Our Acth (4-10), Phe(7)- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports reproducible and reliable results for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate at -20°C. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Amino Acid Composition	Within ±10% of theoretical
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.