Description

5-(4',5'-Dihydroxypentyl)Uracil is a modified nucleobase derivative of uracil, featuring a dihydroxypentyl side chain at the 5-position. This structural modification makes it a valuable synthetic intermediate and building block for advanced pharmaceutical and biochemical research. It is primarily utilized by research institutions and manufacturers in the life sciences sector for developing novel therapeutic agents and nucleotide analogs. The compound is supplied with a focus on high purity and batch-to-batch consistency to meet stringent research and development requirements.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a precursor or reference standard in studies involving DNA/RNA modification, enzyme inhibition, and metabolic pathways.
• Prodrug Development: Serves as a substrate for creating prodrugs with enhanced bioavailability or targeted delivery mechanisms.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study biological processes at the cellular level.
• Nucleotide Chemistry: Intermediate for the preparation of modified nucleotides used in oligonucleotide synthesis and aptamer development.

Basic Information

Product Name	5-(4',5'-Dihydroxypentyl)Uracil
CAS No.	39657-66-4
Molecular Formula	C9H14N2O4
Molecular Weight	214.22 g/mol
Synonyms	5-(1,4-Dihydroxybutyl)uracil; 5-(4,5-Dihydroxypentyl)-2,4(1H,3H)-pyrimidinedione; 5-(1,4-Dihydroxybutyl)pyrimidine-2,4(1H,3H)-dione; Uracil, 5-(4,5-dihydroxypentyl)-; 5-(4,5-Dihydroxypentyl)uracil; 5-(ω,ω'-Dihydroxypentyl)uracil
EINECS	Contact for details

Quality Control

Our 5-(4',5'-Dihydroxypentyl)Uracil is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, the product should be stored in a cool, dry place, ideally at controlled room temperature (15-25°C). For long-term storage, consider desiccants or an inert atmosphere to maintain stability and prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.