Description

3,4,5-Trimethoxybenzene- 1-Sulfonyl Chloride is a versatile and highly reactive sulfonylating agent, a key building block in advanced organic synthesis. Its primary value lies in its ability to introduce the 3,4,5-trimethoxybenzenesulfonyl group, a moiety of significant interest in medicinal chemistry and material science. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the synthesis of sulfonamides, sulfonate esters, and other functionalized molecules.

Application

• Pharmaceutical Intermediate: Critical for synthesizing active pharmaceutical ingredients (APIs), especially sulfonamide-based drugs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides where the trimethoxyphenyl group confers specific biological activity.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating specialty polymers, resins, and functional materials with tailored properties.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for constructing complex molecular architectures and exploring new chemical reactions.
• Dye & Pigment Manufacturing: Employed in the synthesis of specialized dyes and pigments where sulfonyl chloride groups are key for chromophore attachment and solubility modification.
• Ligand & Catalyst Preparation: Useful for modifying ligands and catalysts to enhance their selectivity and performance in catalytic processes.

Basic Information

Product Name	3,4,5-Trimethoxybenzene- 1-Sulfonyl Chloride
CAS No.	39614-62-5
Molecular Formula	C9H11ClO5S
Molecular Weight	266.70 g/mol
Synonyms	1,2,3-Trimethoxy-5-(chlorosulfonyl)benzene; 3,4,5-Trimethoxybenzenesulfonyl chloride; Gallic acid trimethyl ether sulfonyl chloride; Trimethoxybenzenesulfonyl chloride; 3,4,5-Trimethoxybenzene sulfonyl chloride; 3,4,5-Trimethoxybenzenesulphonyl chloride; 5-(Chlorosulfonyl)-1,2,3-trimethoxybenzene
EINECS	Contact for details

Quality Control

Our 3,4,5-Trimethoxybenzene- 1-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for use in fine chemical synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.