Description

L-Alanyl-L-Glutamine is a high-purity, stable dipeptide composed of the amino acids alanine and glutamine. This compound is valued for its superior stability and solubility in aqueous solutions compared to free glutamine, making it an essential component in advanced cell culture and pharmaceutical formulations. It is primarily utilized by manufacturers in the biotechnology, pharmaceutical, and clinical nutrition sectors seeking reliable, high-quality raw materials for sensitive applications.

Application

• Cell Culture Media Supplement: Provides a stable source of glutamine for the growth of mammalian cells, including CHO and HEK293 cells, in biopharmaceutical production.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of more complex peptides and active pharmaceutical ingredients (APIs).
• Clinical Nutrition (Parenteral/Enteral): Used in formulations for total parenteral nutrition (TPN) and specialized medical foods to support patient nitrogen balance and recovery.
• Stem Cell Research: Employed in media for the cultivation and differentiation of stem cells due to its role in cellular metabolism.
• Vaccine Production: Enhances cell viability and productivity in vaccine manufacturing processes.
• Diagnostic Reagents: A component in certain biochemical assay kits and diagnostic formulations.

Basic Information

Product Name	L-Alanyl-L-Glutamine
CAS No.	39537-23-0
Molecular Formula	C8H15N3O4
Molecular Weight	217.22 g/mol
Synonyms	Ala-Gln; L-Alanyl-L-glutamine; N-L-Alanyl-L-glutamine; Glutamine-Alanine dipeptide; Alanylglutamine; (2S)-2-[(2S)-2-Aminopropanamido]-4-carbamoylbutanoic acid; AGN; L-Ala-L-Gln-OH
EINECS	Contact for details

Quality Control

Our L-Alanyl-L-Glutamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral purity verification, and tests for residual solvents and heavy metals, to ensure it meets stringent specifications for pharmaceutical and cell culture applications. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.5%
Optical Rotation	[α]20/D: +10.0° to +12.0° (c=1 in H2O)
Chiral Purity (HPLC)	≥ 99.0% (L,L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.