Description

H-Glu-Ala-Ala-Oh is a synthetic tripeptide composed of glutamic acid and two alanine residues. This compound is a valuable biochemical building block and research tool, particularly for studying enzyme-substrate interactions and peptide synthesis pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in proteomics and medicinal chemistry.

Application

• Biochemical Research: Used as a model substrate for studying the activity and specificity of proteolytic enzymes like glutamyl endopeptidases.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the synthesis and analysis of more complex peptide-based drug candidates.
• Proteomics & Enzymology: Employed in enzyme kinetics assays to understand cleavage patterns and catalytic mechanisms.
• Peptide Synthesis: Acts as a building block in solid-phase or solution-phase peptide synthesis for constructing larger peptide sequences.
• Academic Research: Utilized in university and institutional labs for teaching and research in biochemistry, molecular biology, and organic chemistry.
• Diagnostic Reagent Formulation: Can be incorporated into diagnostic kits as a component for calibrating enzymatic assays.

Basic Information

Product Name	H-Glu-Ala-Ala-Oh
CAS No.	39534-89-9
Molecular Formula	C11H19N3O6
Molecular Weight	289.29 g/mol
Synonyms	L-Glutamyl-L-alanyl-L-alanine; Glu-Ala-Ala; EAA; Glutamic Acid-Alanine-Alanine; H-Glu-Ala-Ala-OH; L-Glu-L-Ala-L-Ala; N-(L-γ-Glutamyl)-L-alanyl-L-alanine; (2S)-2-[[(2S)-2-[[(4S)-4-amino-4-carboxybutanoyl]amino]propanoyl]amino]propanoic acid
EINECS	Contact for details

Quality Control

Our H-Glu-Ala-Ala-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via mass spectrometry and IR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.