Description

Insulin, Desoctapeptide- CAS NO 39416-70-1 is a synthetic peptide fragment derived from the B-chain of insulin, specifically lacking the first eight amino acids (B1-B8). This compound is of significant value in biochemical and pharmaceutical research as a model substrate for studying insulin metabolism, receptor interactions, and the development of novel therapeutic analogs. It is primarily required by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in diabetes research, peptide chemistry, and metabolic studies.

Application

• Biochemical Research: Used as a critical reference standard and substrate in studies of insulin's structure-activity relationship (SAR) and metabolic pathways.
• Pharmaceutical Development: Serves as a key intermediate or starting material in the research and synthesis of novel insulin analogs and peptide-based therapeutics.
• Enzymology Studies: Employed as a specific substrate for investigating the activity and kinetics of insulin-degrading enzyme (IDE) and other proteases.
• Receptor Binding Assays: Utilized in competitive binding experiments to characterize insulin receptor affinity and signaling mechanisms.
• Quality Control: Acts as a system suitability standard in analytical methods (e.g., HPLC, MS) for the characterization of insulin and related products.
• Educational Purposes: Used in advanced academic settings for teaching principles of endocrinology, peptide chemistry, and protein engineering.

Basic Information

Product Name	Insulin, Desoctapeptide- CAS NO 39416-70-1
CAS No.	39416-70-1
Molecular Formula	C148H224N42O45S4
Molecular Weight	~3390.8 g/mol
Synonyms	Desoctapeptide Insulin; B(9-30)-peptide (porcine); Insulin B-chain (9-30); Des-(B1-B8)-insulin; Insulin B-Chain Fragment (9-30); Porcine Desoctapeptide Insulin; [Des-B1-B8]-Insulin; Insulin (Des-Octapeptide B-Chain)
EINECS	Contact for details

Quality Control

Our Insulin, Desoctapeptide is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. Due to its hygroscopic nature, the product should be kept in a dry environment. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.