Description

Distamycin CAS NO 39389-47-4 is a potent antiviral and antitumor antibiotic belonging to the class of pyrrole-amidine oligomers. This compound is significant for its ability to bind selectively to the minor groove of DNA, making it a valuable tool in biochemical research and a lead compound for therapeutic development. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on oncology, virology, and molecular biology.

Application

• Biochemical Research: Used as a specific DNA minor groove binding agent to study protein-DNA interactions, gene regulation, and chromatin structure.
• Antiviral Studies: Serves as a reference compound in the research and screening of antiviral agents, particularly against herpes viruses.
• Oncology Research: Investigated for its antitumor properties and as a model compound for developing novel chemotherapeutic agents that target DNA.
• Molecular Probe Development: Acts as a core structure for creating fluorescent probes and conjugates used in cellular imaging and diagnostic assays.
• Enzyme Inhibition Studies: Utilized to inhibit certain DNA-binding enzymes, aiding in the mechanistic study of transcription and replication.

Basic Information

Product Name	Distamycin
CAS No.	39389-47-4
Molecular Formula	C22H29N9O5
Molecular Weight	499.53 g/mol
Synonyms	Distamycin A; Berenil; Distacin; NSC-38280; 1-Methyl-4-[[1-methyl-4-[[1-methyl-4-[(methylamino)carbonyl]-1H-pyrrol-2-yl]carbonyl]-1H-pyrrol-2-yl]carbonyl]-1H-pyrrole-2-carboxamide; 2-Carbamoyl-1-methylpyrrole-4-carboxylic acid (1-methyl-4-[(1-methyl-4-[(methylamino)carbonyl]pyrrole-2-carbonyl]pyrrole-2-carbonyl]pyrrole-2-carbonyl] ester; Netropsin analog; Pyrrole-amidine antibiotic
EINECS	Contact for details

Quality Control

Our Distamycin is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity research-grade standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.