Description

Boc-D-Phg-Osu CAS NO 39249-27-9 is a high-purity, protected amino acid derivative widely used as a critical building block in peptide synthesis. This compound is essential for introducing the non-natural D-phenylglycine residue into peptide chains with high stereochemical fidelity. It is primarily utilized by pharmaceutical R&D teams, CROs, and CDMOs engaged in the development of novel therapeutic peptides, peptidomimetics, and bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key reagent for the efficient incorporation of D-phenylglycine into peptide sequences, enabling the creation of metabolically stable analogs.
• Solution-Phase Peptide Synthesis: Used in classical coupling strategies for constructing complex peptide structures in solution.
• Pharmaceutical Intermediate: Serves as a vital intermediate in the synthesis of active pharmaceutical ingredients (APIs) for various therapeutic areas.
• Peptidomimetic Research: Facilitates the design and synthesis of peptide-like molecules with enhanced pharmacological properties.
• Bioconjugation: Can be employed in the site-specific modification of proteins or other biomolecules.
• Academic & Industrial R&D: Supports fundamental research in medicinal chemistry, chemical biology, and structural studies.

Basic Information

Product Name	Boc-D-Phg-Osu
CAS No.	39249-27-9
Molecular Formula	C₁₆H₂₀N₂O₆
Molecular Weight	336.34 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-D-phenylglycine N-hydroxysuccinimide ester; Boc-D-α-phenylglycine-OSu; Boc-D-Phg-OSu; (R)-2-((tert-Butoxycarbonyl)amino)-2-phenylacetic acid 2,5-dioxopyrrolidin-1-yl ester; N-Boc-D-phenylglycine succinimidyl ester; N-Boc-D-Phg-OSu; N-Boc-D-α-phenylglycine N-succinimidyl ester; Boc-D-phenylglycine-OSu ester
EINECS	Contact for details

Quality Control

Our Boc-D-Phg-Osu is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation by IR and NMR spectroscopy. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (D-isomer)
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.