Description

5,6,7,8-Tetrahydro[1,2,4]Triazolo[5,1-B]Quinazolin-9(4H)-One is a high-purity, fused heterocyclic compound that serves as a critical advanced pharmaceutical intermediate. This specialized chemical is valued for its unique molecular scaffold, which is integral to the research and development of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules, particularly for central nervous system and metabolic disorder targets.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Reagent: Employed in the construction of complex polycyclic heterocyclic systems for academic and industrial research.
• Biochemical Tool Compound: Serves as a reference standard or probe in biochemical assays to study specific enzyme or receptor interactions.
• Fine Chemical Production: Utilized in the multi-step synthesis of high-value, low-volume specialty chemicals for advanced applications.

Basic Information

Product Name	5,6,7,8-Tetrahydro[1,2,4]Triazolo[5,1-B]Quinazolin-9(4H)-One
CAS No.	39247-61-5
Molecular Formula	C10H10N4O
Molecular Weight	202.21 g/mol
Synonyms	5,6,7,8-Tetrahydro[1,2,4]triazolo[5,1-b]quinazolin-9(4H)-one; 4H-5,6,7,8-Tetrahydro[1,2,4]triazolo[5,1-b]quinazolin-9-one; 39247-61-5; Triazolotetrahydroquinazolinone; Tetrahydrotriazoloquinazolinone; THTQ; [1,2,4]Triazolo[5,1-b]quinazolin-9(4H)-one, 5,6,7,8-tetrahydro-
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydro[1,2,4]Triazolo[5,1-B]Quinazolin-9(4H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure product stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.