Description

β,β-Difluoro-α-Methyl-Benzeneethanamine is a specialized fluorinated amine building block of significant interest in advanced organic synthesis. Its unique structure, featuring a difluoromethyl group adjacent to an amine, makes it a valuable precursor for introducing fluorine motifs into target molecules, which can dramatically alter their physicochemical and biological properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, metabolic diseases, and oncology.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the difluoro moiety can enhance bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Incorporated into specialty polymers or liquid crystals to modify thermal stability, solubility, and electronic properties.
• Fluorine Chemistry Research: An essential building block for academic and industrial research focused on exploring new C-F bond formation reactions and the stereoelectronic effects of fluorine.

Basic Information

Product Name	β,β-Difluoro-α-Methyl-Benzeneethanamine
CAS No.	39038-72-7
Molecular Formula	C9H11F2N
Molecular Weight	171.19 g/mol
Synonyms	2-(Difluoromethyl)-1-phenylethylamine; 1-Phenyl-2-(difluoromethyl)ethylamine; α-Methyl-β,β-difluorophenethylamine; Benzenemethanamine, β,β-difluoro-α-methyl-; (RS)-2-(Difluoromethyl)-1-phenylethylamine; (±)-2-(Difluoromethyl)-1-phenylethylamine; 39038-72-7; β,β-Difluoro-α-methylphenethylamine
EINECS	Contact for details

Quality Control

Our β,β-Difluoro-α-Methyl-Benzeneethanamine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, guaranteeing consistency and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining under an inert atmosphere to preserve optimal quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.