Description

2-Aminohistidine is a specialized, non-proteinogenic amino acid derivative of histidine, featuring an additional amino group on the imidazole ring. This unique structural modification makes it a valuable building block and research chemical for advanced biochemical and pharmaceutical applications. It is primarily utilized by research institutions and manufacturers in the life sciences sector for developing novel compounds, studying enzyme mechanisms, and exploring metabolic pathways.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis of novel drug candidates, particularly those targeting neurological or metabolic disorders.
• Biochemical Research: Used as a probe or substrate in enzymatic studies to investigate the function and inhibition of histidine-decarboxylase and related enzymes.
• Peptide Synthesis: Acts as a modified amino acid residue for incorporating unique properties into synthetic peptides for drug discovery and diagnostic applications.
• Metabolite & Biomarker Studies: Employed in analytical research as a reference standard for the identification and quantification of related metabolites in biological samples.
• Nutritional Science Research: Investigated for its potential role and effects in advanced nutritional and metabolic studies.

Basic Information

Product Name	2-Aminohistidine
CAS No.	39037-22-4
Molecular Formula	C6H10N4O2
Molecular Weight	170.17 g/mol
Synonyms	2-Amino-L-histidine; L-2-Aminohistidine; (2S)-2-Amino-2-(2-amino-1H-imidazol-4-yl)acetic acid; 2,2'-Diaminohistidine; Histidine, 2-amino-; 4-(2-Amino-2-carboxyethyl)-2-aminoimidazole
EINECS	Contact for details

Quality Control

Our 2-Aminohistidine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.