Description

H-Gly-Gly-Sar-Oh CAS NO 38937-80-3 is a specialized tripeptide derivative, specifically a glycine-glycine-sarcosine sequence with a free carboxylic acid terminus. This compound serves as a crucial building block and research tool in advanced peptide synthesis and biochemical studies. It is primarily utilized by pharmaceutical researchers, biotechnology companies, and academic institutions engaged in peptide-based drug discovery, proteomics, and enzyme substrate studies.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of more complex therapeutic peptides and peptidomimetics.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for proteases and peptidases.
• Proteomics & Mass Spectrometry: Serves as a standard or reference compound for method development and calibration in analytical workflows.
• Structure-Activity Relationship (SAR) Studies: Employed to investigate the role of the sarcosine residue on peptide conformation, stability, and biological activity.
• Cosmetic Peptide Synthesis: Potential raw material for the development of bioactive peptides used in skincare formulations.
• Academic & Contract Research: Fundamental reagent for teaching and research in university and CRO laboratories focused on peptide chemistry.

Basic Information

Product Name	H-Gly-Gly-Sar-Oh
CAS No.	38937-80-3
Molecular Formula	C7H13N3O4
Molecular Weight	203.20 g/mol
Synonyms	Glycyl-glycyl-sarcosine; Gly-Gly-Sar-OH; H-Gly-Gly-N-methylglycine-OH; N-(N-Glycylglycyl)-N-methylglycine; GGS-OH; Tripeptide GGS; 2-[[2-[(2-Aminoacetyl)amino]acetyl]-methylamino]acetic acid
EINECS	Contact for details

Quality Control

Our H-Gly-Gly-Sar-Oh is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and heavy metals. Certificates of Analysis (COA) are provided with every shipment, detailing all specifications and test results to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.