Description

D-Trp-NH2 is a high-purity, non-natural D-isomer derivative of the amino acid tryptophan, specifically the tryptophanamide form. This chiral building block is essential for advanced pharmaceutical research and peptide synthesis, where stereochemical control is critical for biological activity. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers developing novel therapeutic peptides, peptidomimetics, and biochemical probes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate the D-tryptophan residue, which can enhance metabolic stability and alter receptor binding profiles.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies, receptor-ligand interaction assays, and metabolic pathway investigations.
• Proteomics & Diagnostics: Can be employed in the synthesis of specialized peptide sequences used as probes, tags, or standards in mass spectrometry and diagnostic assays.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic chemistry, medicinal chemistry, and structural biology.

Basic Information

Product Name	D-Trp-NH2
CAS No.	38689-24-6
Molecular Formula	C11H13N3O
Molecular Weight	203.24 g/mol
Synonyms	D-Tryptophanamide; (R)-2-Amino-3-(1H-indol-3-yl)propanamide; D-α-Aminotryptophanamide; H-D-Trp-NH2; D-Tryptamine-α-carboxamide; (R)-Tryptophanamide; D-Tryptophan amide; D-2-Amino-3-indol-1-ylpropionamide
EINECS	Contact for details

Quality Control

Our D-Trp-NH2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) providing purity, chiral excess, and impurity profiles is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.