Description

H-Phe-Tyr-Nh2 Hcl is a high-purity, protected dipeptide derivative used as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel peptide-based pharmaceuticals and biochemical research tools. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on peptide drug discovery and development.

Application

• Pharmaceutical Intermediate: A crucial building block for the solid-phase and solution-phase synthesis of complex therapeutic peptides and peptidomimetics.
• Biochemical Research: Used in the study of enzyme-substrate interactions, receptor binding assays, and as a standard in analytical method development.
• Peptide Library Construction: Serves as a protected amino acid sequence for generating combinatorial libraries for high-throughput screening in drug discovery.
• API Development: An intermediate in the synthetic pathway for Active Pharmaceutical Ingredients (APIs) targeting metabolic and neurological disorders.
• Conjugate Synthesis: Employed in the creation of peptide-drug conjugates (PDCs) and other bioconjugates for targeted therapies.
• Academic Research: A reagent for graduate-level and post-doctoral research in organic chemistry and medicinal chemistry departments.

Basic Information

Item	Details
Product Name	H-Phe-Tyr-Nh2 Hcl
CAS No.	38678-74-9
Molecular Formula	C18H22N3O4 • HCl
Molecular Weight	381.85 g/mol (Free base: 344.39 g/mol)
Synonyms	H-Phe-Tyr-NH2 hydrochloride; L-Phenylalanyl-L-tyrosinamide hydrochloride; Fmoc-Phe-Tyr-NH2 (precursor); N-[(2S)-1-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-phenylpropan-2-yl]formamide hydrochloride; Phe-Tyr-amide HCl; Boc-Phe-Tyr-NH2•HCl (related); Z-Phe-Tyr-NH2 (related); Peptide Synthesis Building Block PYT-01 (example trade name)
EINECS	Contact for details

Quality Control

Our H-Phe-Tyr-Nh2 Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and NMR for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) for long-term stability. This material is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere (nitrogen or argon) after each use to prevent degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Total)	≥ 99.0%
Optical Rotation	[α]²⁰D: Specific range provided on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.