Description

H-Phe-Gly-Nh2 Hcl is a protected dipeptide building block, specifically the hydrochloride salt of phenylalanylglycinamide. This compound is a crucial intermediate in solid-phase peptide synthesis (SPPS) and other advanced chemical syntheses, offering high purity and reliable reactivity. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers developing novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex therapeutic peptides and peptidomimetics.
• Biochemical Research: Used in academic and industrial research to study peptide structure, function, and metabolism.
• Solid-Phase Peptide Synthesis (SPPS): An essential protected amino acid derivative for the sequential assembly of peptide chains on resin.
• Combinatorial Chemistry: Employed in libraries for drug discovery and screening of bioactive compounds.
• Proteomics & Diagnostics: Can be used in the development of enzyme substrates, inhibitors, or labeled probes for diagnostic assays.

Basic Information

Product Name	H-Phe-Gly-Nh2 Hcl
CAS No.	38678-61-4
Molecular Formula	C11H16N3O2•HCl
Molecular Weight	259.72 g/mol
Synonyms	L-Phenylalanylglycinamide hydrochloride; Phe-Gly-NH2•HCl; F-G-NH2•HCl; N-[(Benzyloxy)carbonyl]-L-phenylalanylglycinamide hydrochloride; Z-Phe-Gly-NH2 HCl; H-Phenylalanine-Glycinamide hydrochloride; (S)-2-Amino-N-(2-amino-2-oxoethyl)-3-phenylpropanamide hydrochloride; Protected dipeptide amide hydrochloride
EINECS	Contact for details

Quality Control

Our H-Phe-Gly-Nh2 Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for pharmaceutical research and synthesis. Certificates of Analysis (COA) with detailed chromatograms are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.