Description

2,2-Dimethylpropionic Acid (2R)-2,3,3Aβ,9Aβ-Tetrahydro-6-Oxo-2α-[(Pivaloyloxy)Methyl]-6H-Furo[2',3':4,5]Oxazolo[3,2-A]Pyrimidin-3β-Yl Ester is a high-purity, complex organic ester derivative of pivalic acid, designed for advanced chemical synthesis. This compound is a critical pharmaceutical intermediate, valued for its specific stereochemistry and functional groups that enable the construction of sophisticated active pharmaceutical ingredients (APIs). It is essential for research institutions and manufacturers in the pharmaceutical and fine chemical sectors requiring precise molecular building blocks.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug molecules, particularly in antiviral or antibiotic research.
• Advanced Organic Synthesis: Used in research and development for constructing fused heterocyclic systems common in medicinal chemistry.
• Process Chemistry: Serves as a protected or functionalized intermediate in the scale-up and optimization of API manufacturing processes.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Academic & Industrial R&D: Utilized in exploratory chemistry for developing new synthetic methodologies and novel chemical entities.

Basic Information

Item	Details
Product Name	2,2-Dimethylpropionic Acid (2R)-2,3,3Aβ,9Aβ-Tetrahydro-6-Oxo-2α-[(Pivaloyloxy)Methyl]-6H-Furo[2',3':4,5]Oxazolo[3,2-A]Pyrimidin-3β-Yl Ester
CAS No.	38642-36-3
Molecular Formula	C18H24N2O7
Molecular Weight	380.40 g/mol
Synonyms	(2R)-2,3,3aβ,9aβ-Tetrahydro-6-oxo-2α-[(pivaloyloxy)methyl]-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-3β-yl 2,2-dimethylpropanoate; Pivalic Acid Ester Derivative; Furooxazolopyrimidine Ester; CAS 38642-36-3; (R)-enantiomer of the specified furooxazolopyrimidine pivalate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high chemical purity. Quality is verified through comprehensive analytical techniques including HPLC, chiral analysis, and NMR spectroscopy. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.