Description

2,2-Dimethylpropionic Acid (2R)-2,3,3Aβ,9Aβ-Tetrahydro-2α-(Hydroxymethyl)-6-Oxo-6H-Furo[2',3':4,5]Oxazolo[3,2-A]Pyrimidin-3β-Yl Ester is a complex, high-purity organic ester with a fused heterocyclic structure. This compound is of significant interest in advanced pharmaceutical synthesis, particularly as a sophisticated chiral building block or synthetic intermediate for active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of complex drug molecules, particularly those targeting the central nervous system or as enzyme inhibitors.
• Advanced Organic Synthesis: Used in multi-step synthetic routes to construct intricate polycyclic frameworks found in natural products and bioactive compounds.
• Medicinal Chemistry Research: Serves as a valuable scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic pathways for potential new chemical entities (NCEs).
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	2,2-Dimethylpropionic Acid (2R)-2,3,3Aβ,9Aβ-Tetrahydro-2α-(Hydroxymethyl)-6-Oxo-6H-Furo[2',3':4,5]Oxazolo[3,2-A]Pyrimidin-3β-Yl Ester
CAS No.	38642-35-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Pivalic Acid (2R)-2,3,3aβ,9aβ-Tetrahydro-2α-(Hydroxymethyl)-6-oxo-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-3β-yl Ester; Trimethylacetic Acid (2R)-2,3,3aβ,9aβ-Tetrahydro-2α-(Hydroxymethyl)-6-oxo-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-3β-yl Ester; (2R)-3β-Pivaloyloxy-2α-(hydroxymethyl)-2,3,3aβ,9aβ-tetrahydro-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one; 38642-35-2; Furo[2',3':4,5]oxazolo[3,2-a]pyrimidine derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for advanced pharmaceutical intermediates. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to verify identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. Production can be aligned with cGMP (current Good Manufacturing Practice) guidelines for applications requiring the highest level of quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. For long-term stability, storage at controlled room temperature (15-25°C) is recommended. Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.