Description

5-Chloro-2-Methoxy-Pyrimidine is a versatile pyrimidine derivative, a crucial heterocyclic building block in advanced organic synthesis. Its value lies in its dual functionality, offering reactive sites for nucleophilic aromatic substitution and metal-catalyzed cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, serving as a key intermediate in the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer drug discovery programs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where the pyrimidine core is a common structural motif.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in homogeneous catalysis and material science.
• Organic Electronic Materials: Acts as a building block for the synthesis of novel organic semiconductors and light-emitting materials.
• Chemical Research & Development: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and exploring new reaction pathways.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals for various high-value industrial applications.

Basic Information

Product Name	5-Chloro-2-Methoxy-Pyrimidine
CAS No.	38373-44-3
Molecular Formula	C5H5ClN2O
Molecular Weight	144.56 g/mol
Synonyms	2-Methoxy-5-chloropyrimidine; 5-Chloro-2-methoxypyrimidine; 5-Chloro-2-pyrimidinyl methyl ether; Pyrimidine, 5-chloro-2-methoxy-; 5-Chloro-2-methoxy-1,3-diazine; 38373-44-3; 5-Chloro-2-methoxypyrimidine
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Methoxy-Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee reliable performance in your sensitive synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.