Description

Pyr-His(1-Me)-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-Nh2 Tfa is a synthetic peptide derivative, specifically a modified analog of the growth hormone-releasing hormone (GHRH) fragment. This compound is of significant interest for its role in biochemical research and pharmaceutical development, particularly in studies related to endocrine function and peptide hormone activity. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in metabolic and hormonal pathway investigations.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of growth hormone secretagogue receptors (GHSR) and GHRH signaling pathways.
• Pharmaceutical R&D: Serves as a key intermediate or lead compound in the development of novel therapeutics targeting growth hormone deficiencies and related metabolic disorders.
• In Vitro Diagnostics: Employed in the development and calibration of immunoassays and bioanalytical tests designed to measure GHRH-like activity.
• Peptide Chemistry Studies: Utilized as a model compound for investigating structure-activity relationships (SAR), stability, and modification techniques of bioactive peptides.
• Academic Research: Applied in university and institutional labs for fundamental research in endocrinology, neuroendocrinology, and peptide pharmacology.

Basic Information

Product Name	Pyr-His(1-Me)-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-Nh2 Tfa
CAS No.	38343-58-7
Molecular Formula	C66H91N19O15 • xC2HF3O2
Molecular Weight	~1418.6 g/mol (free base)
Synonyms	GHRH (1-11) amide, 1-Me-His2 analog; Pyr-His(1-Me)-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-amide TFA salt; Modified GHRH Fragment; Growth Hormone-Releasing Hormone Analog; [1-Methyl-His2]-GHRH(1-11)-NH2; GHRH(1-11)-NH2, 1-Me-His2; Peptide G-1; Research Peptide 38343-58-7
EINECS	Contact for details

Quality Control

Our peptide products are manufactured and analyzed under strict quality management systems. Each batch of Pyr-His(1-Me)-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-Nh2 Tfa undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to ensure compliance with your research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Peptide Content	≥ 80.0% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.