Description

(Des-Pyr1)-Lhrh is a synthetic peptide analog of Luteinizing Hormone-Releasing Hormone (LHRH), a key decapeptide in the hypothalamic-pituitary-gonadal axis. This compound is of significant value for advanced research in endocrinology and oncology, serving as a crucial tool for studying hormone regulation and receptor interactions. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on developing novel therapeutic agents and diagnostic tools.

Application

• Biomedical Research: Fundamental studies on the structure-activity relationship (SAR) of LHRH and its receptor binding mechanisms.
• Drug Discovery & Development: Serving as a reference standard or a key intermediate in the synthesis of novel LHRH agonists and antagonists for therapeutic applications.
• Endocrinology Studies: Investigating the regulation of gonadotropin secretion and its role in reproductive biology.
• Oncology Research: Exploring the role of LHRH pathways in hormone-dependent cancers, such as prostate and breast cancer.
• In Vitro Diagnostics (IVD): Potential use as a critical component in the development of immunoassays for hormone level detection.
• Peptide Chemistry: Used as a model compound in methodological development for peptide synthesis, purification, and analysis.

Basic Information

Product Name	(Des-Pyr1)-Lhrh
CAS No.	38280-53-4
Molecular Formula	C55H78N16O12
Molecular Weight	1131.3 g/mol
Synonyms	(Des-Pyr1)-Luteinizing Hormone-Releasing Hormone; (Des-Pyroglutamyl1)-LHRH; LHRH (2-10); Luteinizing Hormone-Releasing Hormone (2-10); pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 (2-10) fragment; Gonadorelin (2-10); LH-RH (2-10); Follicle-Stimulating Hormone-Releasing Hormone (2-10)
EINECS	Contact for details

Quality Control

Our (Des-Pyr1)-Lhrh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as purity by HPLC, amino acid analysis, and mass spectrometry are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., argon or nitrogen) after opening and to allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Amino Acid Analysis	Within ± 10% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.