Description

5-Bromopyrimidine-2-Carbonitrile is a high-value brominated pyrimidine derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a bromine atom and a nitrile group on the pyrimidine ring, makes it an indispensable intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or functionalizing agent for creating specialized polymers and liquid crystals.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce the pyrimidine core into more complex structures.
• Bioconjugation & Probe Development: The reactive bromine and nitrile groups allow for attachment to biomolecules or other scaffolds for creating diagnostic tools or biochemical probes.

Basic Information

Product Name	5-Bromopyrimidine-2-Carbonitrile
CAS No.	38275-57-9
Molecular Formula	C5H2BrN3
Molecular Weight	183.99 g/mol
Synonyms	2-Cyano-5-bromopyrimidine; 5-Bromo-2-pyrimidinecarbonitrile; 5-Bromopyrimidine-2-carbonitrile; 5-Bromo-2-cyanopyrimidine; 38275-57-9; 5-Brom-2-cyanpyrimidin; 5-Bromo-2-pyrimidine carbonitrile
EINECS	Contact for details

Quality Control

Our 5-Bromopyrimidine-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with your specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.