Description

2-Pyrimidinecarbonitrile, 5-Chloro- (9Ci) is a versatile and high-value halogenated pyrimidine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its reactive nitrile and chloro substituents, which allow for selective functionalization to construct complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of nucleoside analogs, kinase inhibitors, and other biologically active pyrimidine-based compounds.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides that incorporate a chloropyrimidine core.
• Material Science Research: Serves as a precursor for creating functionalized polymers, ligands for metal-organic frameworks (MOFs), and other advanced materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes, enzyme inhibitors, and tool compounds for biochemical research.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Pyrimidinecarbonitrile, 5-Chloro- (9Ci)
CAS No.	38275-56-8
Molecular Formula	C5H2ClN3
Molecular Weight	139.54 g/mol
Synonyms	5-Chloropyrimidine-2-carbonitrile; 5-Chloro-2-cyanopyrimidine; 2-Cyano-5-chloropyrimidine; 5-Chloro-2-pyrimidinecarbonitrile; 38275-56-8; 5-Chloropyrimidine-2-carbonitrile (9CI); 5-Chloro-2-pyrimidinecarbonitrile (9CI)
EINECS	Contact for details

Quality Control

Our 2-Pyrimidinecarbonitrile, 5-Chloro- (9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.