Description

5-Bromo-2-Methanesulfonyl-Pyrimidine is a high-purity, functionalized pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic combination of a bromine substituent and a methanesulfonyl group, which act as versatile handles for further chemical modification via cross-coupling and nucleophilic substitution reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reactive probe or linker in the study of biological systems and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Bromo-2-Methanesulfonyl-Pyrimidine
CAS No.	38275-48-8
Molecular Formula	C5H5BrN2O2S
Molecular Weight	237.07 g/mol
Synonyms	5-Bromo-2-(methylsulfonyl)pyrimidine; 2-Methanesulfonyl-5-bromopyrimidine; 5-Bromo-2-pyrimidinyl methyl sulfone; 5-Bromo-2-(methanesulfonyl)pyrimidine; Pyrimidine, 5-bromo-2-(methylsulfonyl)-; 38275-48-8
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Methanesulfonyl-Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high standards, including cGMP-compliant pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.