Description

2-Methylsulfanyl-Pyrimidine-5-Carbonitrile is a versatile heterocyclic building block featuring a pyrimidine core substituted with a nitrile and a methylthio group. This compound matters as a key synthetic intermediate in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a building block for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Dye & Pigment Manufacturing: Acts as an intermediate for synthesizing specialized heterocyclic dyes and colorants.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke chemical synthesis projects.

Basic Information

Item	Details
Product Name	2-Methylsulfanyl-Pyrimidine-5-Carbonitrile
CAS No.	38275-43-3
Molecular Formula	C6H5N3S
Molecular Weight	151.19 g/mol
Synonyms	5-Cyano-2-(methylthio)pyrimidine; 2-(Methylthio)-5-pyrimidinecarbonitrile; 2-Methylmercapto-5-cyanopyrimidine; 2-Methylsulfanylpyrimidine-5-carbonitrile; 2-(Methylsulfanyl)pyrimidine-5-carbonitrile; 2-Methylthio-5-cyanopyrimidine; 5-Pyrimidinecarbonitrile, 2-(methylthio)-; 38275-43-3
EINECS	Contact for details

Quality Control

Our 2-Methylsulfanyl-Pyrimidine-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.