Description

5-Chloro-2-(Methylsulfonyl)Pyrimidine-4-Carboxylic Acid is a high-purity, multi-functional pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its unique sulfonyl and carboxylic acid functionalities make it a versatile intermediate for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for antiviral, anticancer, and kinase inhibitor drugs.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Serves as a reactive handle for bioconjugation and the development of chemical probes and inhibitors.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and development candidates under cGMP conditions.

Basic Information

Product Name	5-Chloro-2-(Methylsulfonyl)Pyrimidine-4-Carboxylic Acid
CAS No.	38275-34-2
Molecular Formula	C7H5ClN2O4S
Molecular Weight	248.64 g/mol
Synonyms	5-Chloro-2-(methylsulfonyl)-4-pyrimidinecarboxylic acid; 4-Pyrimidinecarboxylic acid, 5-chloro-2-(methylsulfonyl)-; 38275-34-2; 5-Chloro-2-methanesulfonylpyrimidine-4-carboxylic acid; 2-Methylsulfonyl-5-chloropyrimidine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-(Methylsulfonyl)Pyrimidine-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates for research and regulated production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.