Description

Cyclo(L-Pro-L-Trp-) is a cyclic dipeptide, also known as a diketopiperazine (DKP), formed from the amino acids L-Proline and L-Tryptophan. This compound is of significant interest in pharmaceutical research and development due to its role as a key structural motif and potential biological activity. It serves as a critical intermediate or reference standard for researchers in medicinal chemistry, peptide synthesis, and biochemistry. The product is identified by the CAS registry number 38136-70-8.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of more complex peptide-based drugs and bioactive molecules.
• Medicinal Chemistry Research: Used as a scaffold or reference compound in drug discovery programs targeting various receptors and enzymes.
• Biochemical Tool: Acts as a standard or inhibitor in enzymatic studies and biochemical assays to investigate biological pathways.
• Peptide Synthesis: Employed in solid-phase and solution-phase peptide synthesis to introduce the cyclic Pro-Trp motif into larger peptide chains.
• Cosmeceutical Research: Investigated for potential applications in skincare formulations due to the bioactive properties of peptide derivatives.
• Academic & Industrial R&D: Utilized in universities and corporate labs for fundamental research on diketopiperazine chemistry and pharmacology.

Basic Information

Product Name	Cyclo(L-Pro-L-Trp-)
CAS No.	38136-70-8
Molecular Formula	C16H17N3O2
Molecular Weight	283.33 g/mol
Synonyms	Cyclo(prolyltryptophanyl); Cyclo(L-Pro-L-Trp); L-Prolyl-L-tryptophan anhydride; 3,6-Bis(indol-3-ylmethyl)-2,5-diketopiperazine (related derivative); DKPs; Diketopiperazine; Pro-Trp DKP; c(Pro-Trp)
EINECS	Contact for details

Quality Control

Our Cyclo(L-Pro-L-Trp-) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity confirmation and identity verification by spectroscopic methods (IR, NMR). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.