Description

S-((2-Chloroethyl)Carbamoyl)Glutathione is a chemically modified derivative of the essential antioxidant glutathione, designed for targeted biochemical research and synthesis. This compound is of significant interest for its role as a potential alkylating agent and its utility in studying glutathione metabolism and detoxification pathways. It serves as a critical intermediate and research tool for pharmaceutical development, toxicology studies, and advanced biochemical research, where precise molecular modification is required.

Application

• Biochemical Research: Used as a key intermediate in studies investigating glutathione-S-transferase (GST) activity, cellular detoxification mechanisms, and redox biology.
• Pharmaceutical Development: Serves as a precursor or model compound in the synthesis and evaluation of novel chemotherapeutic agents and cytoprotective drugs.
• Toxicology Studies: Employed to investigate the metabolic fate and adduct formation of alkylating agents within biological systems.
• Enzyme Inhibition Studies: Acts as a potential inhibitor or substrate analog in enzymatic assays to elucidate reaction mechanisms.
• Reference Standard: Utilized as an analytical standard in HPLC, LC-MS, or NMR for the quantification and identification of related metabolites in complex matrices.

Basic Information

Product Name	S-((2-Chloroethyl)Carbamoyl)Glutathione
CAS No.	38134-58-6
Molecular Formula	C13H21ClN4O7S
Molecular Weight	412.85 g/mol
Synonyms	Glutathione, S-[(2-chloroethyl)carbamoyl]-; S-(2-Chloroethylcarbamoyl)glutathione; NSC 401005; L-Glutathione, S-[(2-chloroethyl)carbamoyl]-; (2S)-2-Amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-{[(2-chloroethyl)carbamoyl]sulfanyl}ethyl]carbamoyl}butanoic acid
EINECS	Contact for details

Quality Control

Our S-((2-Chloroethyl)Carbamoyl)Glutathione is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and determination of residual solvents and moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider conditions of 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.