Description

H-Leu-Gln-Oh CAS NO 38062-69-0 is a high-purity dipeptide derivative, specifically the C-terminal carboxylic acid form of the leucine-glutamine sequence. This compound serves as a critical building block and intermediate in advanced pharmaceutical research and peptide synthesis. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors developing novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediate: A key raw material in the solid-phase and solution-phase synthesis of complex therapeutic peptides and peptidomimetics.
• Biochemical Research: Used as a standard or substrate in enzymatic studies, metabolic pathway analysis, and proteomics research.
• Cosmetic Peptide Synthesis: Incorporated into the development of bioactive peptides for advanced skincare and anti-aging formulations.
• Nutraceutical Development: Serves as a precursor for specialized dietary supplements and bioactive nutrient compounds.
• Chemical Biology Tool: Employed in the design and construction of peptide-based probes, tags, and inhibitors for cellular and molecular biology.
• API Development: An important intermediate in the research and scale-up production of Active Pharmaceutical Ingredients (APIs) with peptide backbones.

Basic Information

Product Name	H-Leu-Gln-Oh
CAS No.	38062-69-0
Molecular Formula	C11H21N3O4
Molecular Weight	259.30 g/mol
Synonyms	L-Leucyl-L-glutamine; Leu-Gln; L-Leu-L-Gln-OH; N-(L-Leucyl)-L-glutamine; H-Leu-Gln-OH; Leucine-glutamine dipeptide; 2-[(2-Amino-4-methylpentanoyl)amino]-4-carbamoylbutanoic acid; L-Leucylglutamine
EINECS	Contact for details

Quality Control

Our H-Leu-Gln-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) documenting identity, purity, and specific impurities are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	-30° to -35° (c=1 in H2O)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.2%
Heavy Metals	≤20 ppm
Single Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.