Description

H-Phe-Phe-Ome Hcl is a protected dipeptide derivative of significant interest in pharmaceutical research and development. This compound serves as a crucial building block in the synthesis of more complex peptides and peptidomimetics, offering researchers a versatile intermediate with defined stereochemistry. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors for drug discovery and process optimization.

Application

• Pharmaceutical Intermediate: A key building block in the solid-phase and solution-phase synthesis of novel therapeutic peptides and peptidomimetics targeting various diseases.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate protease activity and specificity.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of peptide-based drug candidates.
• Process Development: Serves as a reference standard or an intermediate in scaling up and optimizing synthetic routes for active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis, peptide chemistry, and chemical biology.

Basic Information

Product Name	H-Phe-Phe-Ome Hcl
CAS No.	38017-65-1
Molecular Formula	C20H24N2O3 • HCl
Molecular Weight	376.88 g/mol
Synonyms	L-Phenylalanyl-L-phenylalanine methyl ester hydrochloride; Methyl L-phenylalanyl-L-phenylalaninate hydrochloride; Phe-Phe-OMe • HCl; H-Phe-Phe-OMe hydrochloride; F-F-OMe HCl; (S)-Methyl 2-((S)-2-amino-3-phenylpropanamido)-3-phenylpropanoate hydrochloride; N-[(2S)-1-[(2S)-2-Methoxy-1-oxo-2-phenylethyl]amino]-1-oxo-3-phenylpropan-2-yl]benzamide hydrochloride (related IUPAC form)
EINECS	Contact for details

Quality Control

Our H-Phe-Phe-Ome Hcl is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP guidelines, where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.