Description

Pyrimidine, 2-Ethynyl- (9Ci) is a specialized heterocyclic building block featuring an ethynyl substituent on the pyrimidine core. This compound matters as a versatile intermediate for synthesizing more complex molecules, particularly in pharmaceutical research and advanced material science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced active ingredients for crop protection products.
• Material Science Research: Serves as a building block for organic semiconductors, ligands for metal-organic frameworks (MOFs), and other functional materials.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological systems via click chemistry or other bioorthogonal reactions.
• Academic & Industrial R&D: Employed in exploratory chemistry for developing new synthetic methodologies and discovering compounds with unique properties.

Basic Information

Product Name	Pyrimidine, 2-Ethynyl- (9Ci)
CAS No.	37972-24-0
Molecular Formula	C6H4N2
Molecular Weight	104.11 g/mol
Synonyms	2-Ethynylpyrimidine; 2-Pyrimidinylacetylene; Ethynylpyrimidine; 2-Ethynyl-1,3-diazine; 2-Ethynylpyrimidine (9CI); 2-Ethynyl-pyrimidine
EINECS	Contact for details

Quality Control

Our Pyrimidine, 2-Ethynyl- (9Ci) is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.