Description

3-Chloro-4-Trifluoromethylphenol is a versatile halogenated phenolic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, combining chlorine and trifluoromethyl substituents on the phenol ring, imparts valuable properties for creating high-performance materials and active ingredients. This intermediate is essential for manufacturers in the agrochemical and pharmaceutical sectors, where it is used to develop novel active compounds with enhanced efficacy and stability.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of advanced herbicides, fungicides, and plant growth regulators, leveraging its bio-active phenolic structure.
• Pharmaceutical Building Block: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for compounds requiring halogenated aromatic motifs.
• Liquid Crystal & Polymer Chemistry: Serves as a monomer or modifying agent in the production of specialty polymers and liquid crystal materials for electronic displays.
• Dye & Pigment Synthesis: Acts as an intermediate in the manufacture of complex dyes and organic pigments, where the trifluoromethyl group can alter color fastness and solubility.
• Organic Synthesis Reagent: Employed in various coupling reactions and as a protecting group or directing agent in complex multi-step synthetic routes.

Basic Information

Product Name	3-Chloro-4-Trifluoromethylphenol
CAS No.	37900-81-5
Molecular Formula	C7H4ClF3O
Molecular Weight	196.55 g/mol
Synonyms	3-Chloro-4-(trifluoromethyl)phenol; 4-Trifluoromethyl-3-chlorophenol; 3-Chloro-alpha,alpha,α-trifluoro-p-cresol; Phenol, 3-chloro-4-(trifluoromethyl)-; 3-Chloro-4-trifluoromethyl phenol; 3-Chloro-4-(trifluoromethyl)phenol; 3-Chloro-4-trifluoromethyl hydroxybenzene
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-4-Trifluoromethylphenol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	40 - 44 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.