Description

Oxytocin, 2-L-Tryptophan- CAS NO 37883-08-2 is a synthetic analogue of the neuropeptide hormone oxytocin, specifically modified at the 2-position with an L-tryptophan residue. This modification is significant for research into the structure-activity relationships of oxytocin and its receptor interactions. It is primarily required by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on neuroendocrinology, peptide chemistry, and therapeutic development.

Application

• Pharmaceutical Research & Development: A key intermediate or reference standard in the synthesis and study of novel oxytocin analogues for potential therapeutic applications.
• Neuroendocrine Studies: Used in biochemical and pharmacological research to investigate the binding affinity, selectivity, and functional activity at oxytocin and vasopressin receptors.
• Peptide Chemistry & Structure-Activity Relationship (SAR): Serves as a critical tool for understanding how specific amino acid substitutions affect the biological potency and metabolic stability of peptide hormones.
• Biochemical Reagent: Employed as a high-purity reagent in enzymatic assays, cell-based studies, and signal transduction pathway analysis related to oxytocin's physiological roles.
• Reference Standard: Used for analytical method development, validation, and quality control (HPLC, MS) in the production of peptide-based active pharmaceutical ingredients (APIs).

Basic Information

Item	Detail
Product Name	Oxytocin, 2-L-Tryptophan- CAS NO 37883-08-2
CAS No.	37883-08-2
Molecular Formula	C₅₃H₆₇N₁₁O₁₂S₂
Molecular Weight	1106.3 g/mol
Synonyms	2-L-Tryptophan-oxytocin; [2-L-Trp]-Oxytocin; Oxytocin (2-L-Trp); 2-Tryptophan-oxytocin; 2-Trp-Oxytocin; 1-{6-Amino-2-[(2-amino-2-oxoethyl)amino]-1-oxohexyl}-L-prolyl-L-leucylglycyl-L-asparaginyl-L-cysteinyl-L-α-glutamyl-L-isoleucyl-L-cysteinyl-L-tryptophanamide cyclic (1→6)-disulfide; [2-L-Tryptophan]oxytocin
EINECS	Contact for details

Quality Control

Our Oxytocin, 2-L-Tryptophan- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all test results against established specifications to ensure consistency and reliability for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.