Description

N(3)-Histidylriboflavin is a specialized riboflavin derivative where the vitamin is covalently linked to the amino acid histidine. This unique molecular structure is of significant interest in biochemical research for studying flavoprotein mechanisms and enzyme cofactor interactions. It serves as a critical reference standard and intermediate for researchers and manufacturers in the pharmaceutical and nutraceutical industries, particularly those developing advanced enzyme models or investigating vitamin B2 metabolism.

Application

• Biochemical Research: Used as a reference standard and probe for studying flavin-dependent enzymes and electron transfer processes.
• Pharmaceutical Intermediates: Serves as a key synthetic intermediate in the development of novel pharmaceutical compounds and targeted drug delivery systems.
• Nutraceutical Development: Investigated for potential applications in advanced nutritional supplements and functional food ingredients with enhanced bioavailability.
• Enzyme Modeling: Essential for creating artificial enzyme models and understanding cofactor-protein binding interactions in vitro.
• Diagnostic Reagent Manufacturing: Employed in the production of specialized diagnostic kits and reagents for clinical and research laboratories.

Basic Information

Product Name	N(3)-Histidylriboflavin
CAS No.	37854-44-7
Molecular Formula	C25H30N8O7
Molecular Weight	554.56 g/mol
Synonyms	Histidylriboflavin; Riboflavinylhistidine; Flavinylhistidine; N3-Histidyl-riboflavin; Vitamin B2 Histidine Conjugate; 1-Histidylriboflavin; Lumiflavin Histidine Derivative; 7,8-Dimethyl-10-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]benzo[g]pteridine-2,4(3H,10H)-dione histidine conjugate
EINECS	Contact for details

Quality Control

Our N(3)-Histidylriboflavin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports your need for reliable and consistent performance in sensitive applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.