Description

Arg-Pro-Hyp-Gly-Phe-Ser-Pro-Phe-Arg is a synthetic nonapeptide, a fragment of the collagen α-1(I) chain, widely recognized for its role in biochemical research and development. This compound is a critical tool for studying collagen metabolism, protein-protein interactions, and the mechanisms of various physiological processes. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for applications ranging from drug discovery to biomimetic material design.

Application

• Biochemical Research: Used as a standard or substrate in enzymatic assays to study collagenase and other protease activities.
• Pharmaceutical Development: Serves as a key intermediate or reference compound in the development of therapies targeting collagen-related disorders, such as fibrosis and osteoarthritis.
• Cell Culture & Tissue Engineering: Employed to functionalize surfaces or hydrogels to promote cell adhesion and study cell-matrix interactions in vitro.
• Antibody Production: Acts as an immunogen for generating specific antibodies against collagen sequences for diagnostic and research purposes.
• Biomimetic Materials: Incorporated into synthetic polymers or coatings to impart bioactivity and mimic the properties of natural collagen.
• Quality Control: Used as a reference standard in analytical laboratories for the identification and quantification of collagen-derived peptides.

Basic Information

Product Name	Arg-Pro-Hyp-Gly-Phe-Ser-Pro-Phe-Arg
CAS No.	37642-65-2
Molecular Formula	C53H78N18O13
Molecular Weight	1151.3 g/mol
Synonyms	Collagen α-1(I) chain fragment (residues 1036-1044); (Gly-Pro-Hyp)3; Gly-Pro-Hyp-Gly-Pro-Hyp-Gly-Pro-Hyp; GPO Peptide; Collagen Mimetic Peptide (CMP); (Gly-Pro-Hyp)n; Proline-Hydroxyproline-Glycine Peptide; P-Hyp-G Peptide
EINECS	Contact for details

Quality Control

Our Arg-Pro-Hyp-Gly-Phe-Ser-Pro-Phe-Arg is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment to ensure traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. For long-term storage, consider desiccation or storage under an inert atmosphere due to its hygroscopic nature. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Conforms to theoretical values
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.