Description

4'''-Deglycosyllividomycin A is a chemically modified derivative of the lividomycin antibiotic, representing a key intermediate in pharmaceutical research and development. This compound is valued for its role in structure-activity relationship (SAR) studies, enabling the synthesis of novel antimicrobial agents with potentially improved efficacy and reduced toxicity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of next-generation antibiotics targeting resistant bacterial strains.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthetic pathway for novel aminoglycoside and lividomycin-derived antibiotics.
• Antimicrobial Research: Used in biochemical and microbiological assays to study mechanisms of action and resistance against Gram-negative and Gram-positive bacteria.
• Structure-Activity Relationship (SAR) Studies: Essential for modifying the glycosidic moiety to optimize pharmacokinetic properties, such as absorption and tissue penetration.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation in antibiotic analysis.
• Academic & Institutional Research: Supports fundamental research in medicinal chemistry and molecular biology focused on overcoming antibiotic resistance.

Basic Information

Product Name	4'''-Deglycosyllividomycin A
CAS No.	37636-51-4
Molecular Formula	C17H32N6O9
Molecular Weight	464.47 g/mol
Synonyms	4'''-De-O-glycosyllividomycin A; Lividomycin A 4'''-deglycosyl derivative; Antibiotic SF-767A derivative; 5-Deoxy-2-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-3-C-[(1S)-4-amino-1-(aminomethyl)-2-hydroxybutyl]-1-N-[(2S)-4-amino-2-hydroxybutanoyl]-1,3,5-trideoxy-D-ribo-hexitol; 1-N-[(2S)-4-Amino-2-hydroxybutanoyl]-5-deoxy-2-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-3-C-[(1S)-4-amino-1-(aminomethyl)-2-hydroxybutyl]-1,3,5-trideoxy-D-ribo-hexitol
EINECS	Contact for details

Quality Control

Our 4'''-Deglycosyllividomycin A is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. A Certificate of Analysis (COA) detailing all test results is provided to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.