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n-[[4-(Dimethylamino)Phenyl]Methylene]-L-Val-L-Ile-L-Ala-Oet CAS NO 37580-35-1


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CAS No.:37580-35-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-[[4-(Dimethylamino)Phenyl]Methylene]-L-Val-L-Ile-L-Ala-Oet is a synthetic tripeptide derivative featuring a photolabile protecting group. This compound is of significant value in advanced peptide synthesis and pharmaceutical research, particularly for its role in light-directed, spatially addressable chemical synthesis. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers developing novel peptide-based therapeutics, diagnostic tools, and photochemical applications.

Application

  • Photolabile Protecting Group in Solid-Phase Peptide Synthesis (SPPS): Used for the temporary protection of amino acids, allowing for selective deprotection using light (photolysis) to enable complex, multi-step peptide assembly.
  • Research Chemical for Novel Drug Discovery: Serves as a key intermediate or building block in the research and development of new peptide-based pharmaceuticals and bioactive compounds.
  • Synthesis of Peptide Libraries: Essential for creating spatially defined combinatorial peptide libraries used in high-throughput screening for drug candidates and biological probes.
  • Development of Diagnostic Reagents: Can be utilized in the design and synthesis of peptide-conjugated markers or probes for diagnostic assays.
  • Material Science Research: Investigated for potential use in creating light-responsive biomaterials or smart polymer surfaces.

Basic Information

Product Name n-[[4-(Dimethylamino)Phenyl]Methylene]-L-Val-L-Ile-L-Ala-Oet
CAS No. 37580-35-1
Molecular Formula C24H38N4O4
Molecular Weight 446.59 g/mol
Synonyms N-[(4-Dimethylaminophenyl)methylene]-L-valyl-L-isoleucyl-L-alanine ethyl ester; (S)-Ethyl 2-((S)-2-((S)-2-((4-(dimethylamino)benzylidene)amino)-3-methylbutanamido)-3-methylpentanamido)propanoate; L-Val-L-Ile-L-Ala-Oet NVOC derivative; NVOC-Val-Ile-Ala-OEt; Photolabile NVOC-protected tripeptide ester; 6-Nitroveratryloxycarbonyl-type protecting group reagent; Contact for additional synonyms.
EINECS Contact for details

Quality Control

Our n-[[4-(Dimethylamino)Phenyl]Methylene]-L-Val-L-Ile-L-Ala-Oet is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item Specification
Appearance White to off-white powder or crystalline solid
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 95.0% (Area %)
Water Content (KF) ≤ 2.0%
Specific Rotation Contact for details
Heavy Metals < 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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