Description

n-(3-Pyridinylmethylene)-L-Val-L-Ile-L-Ala-Oet is a synthetic tripeptide derivative featuring a pyridinylmethylene moiety. This compound is of significant interest in advanced pharmaceutical research and development, particularly as a specialized intermediate or building block for novel drug candidates. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of peptide-based therapeutics and protease inhibitors. Its specific structure offers potential for modulating biological activity and pharmacokinetic properties.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and synthesis of novel peptide-based drug candidates.
• Protease Inhibitor Research: Used in the development and study of inhibitors targeting specific proteolytic enzymes.
• Medicinal Chemistry: Employed as a scaffold for structure-activity relationship (SAR) studies to optimize drug-like properties.
• Bioconjugation: Potential use in creating peptide-drug conjugates or labeled peptides for diagnostic applications.
• Chemical Biology: Acts as a tool compound for probing enzyme-substrate interactions and biological pathways.
• Reference Standard: Used as an analytical standard in quality control and method development for related pharmaceutical products.

Basic Information

Product Name	n-(3-Pyridinylmethylene)-L-Val-L-Ile-L-Ala-Oet
CAS No.	37580-32-8
Molecular Formula	C24H36N4O5
Molecular Weight	460.57 g/mol
Synonyms	L-Val-L-Ile-L-Ala-Oet N-(3-Pyridinylmethylene); Ethyl L-alanyl-L-isoleucyl-L-valinate N-(3-pyridinylmethylene); N-[(3-Pyridinyl)methylidene]-L-valyl-L-isoleucyl-L-alanine ethyl ester; (S)-Ethyl 2-((S)-2-((S)-2-((pyridin-3-ylmethylene)amino)-3-methylbutanamido)-3-methylpentanamido)propanoate; Peptide derivative CAS 37580-32-8; Pyridine-containing tripeptide ester
EINECS	Contact for details

Quality Control

Our n-(3-Pyridinylmethylene)-L-Val-L-Ile-L-Ala-Oet is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to ensure stereochemical integrity. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing batch-specific results. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.