Description

n-[(4-Nitrophenyl)Methylene]-L-Val-L-Ile-L-Ala-Oet is a synthetic tripeptide derivative featuring a (4-nitrophenyl)methylene protecting group. This compound is a critical intermediate in advanced peptide synthesis, offering precise control over molecular architecture for research and development. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing novel bioactive peptides and peptidomimetics.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in academic and industrial laboratories for studying peptide structure-activity relationships (SAR) and enzyme-substrate interactions.
• Protease Inhibitor Development: Acts as a precursor or model compound in the design and screening of inhibitors for proteolytic enzymes.
• Peptidomimetic Synthesis: Provides a scaffold for creating modified peptides with enhanced stability, bioavailability, or target specificity.
• Custom Peptide Services: Employed by CROs and CDMOs for the contract manufacturing of specialized, non-standard peptide sequences for clients.

Basic Information

Item	Details
Product Name	n-[(4-Nitrophenyl)Methylene]-L-Val-L-Ile-L-Ala-Oet
CAS No.	37580-25-9
Molecular Formula	C24H36N4O7
Molecular Weight	492.57 g/mol
Synonyms	N-[(4-Nitrophenyl)methylene]-L-valyl-L-isoleucyl-L-alanine ethyl ester; (4-Nitrobenzylidene)-L-Val-L-Ile-L-Ala-OEt; L-Alanine, N-[(4-nitrophenyl)methylene]-L-valyl-L-isoleucyl-, ethyl ester; Ethyl N-[(4-nitrophenyl)methylidene]-L-valyl-L-isoleucyl-L-alaninate; Peptide derivative CAS 37580-25-9; Val-Ile-Ala-OEt (4-Nitrophenyl)methylene derivative; Tripeptide protecting group intermediate
EINECS	Contact for details

Quality Control

Our n-[(4-Nitrophenyl)Methylene]-L-Val-L-Ile-L-Ala-Oet is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to ensure enantiomeric integrity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with your research or cGMP guidelines for non-clinical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept in a desiccated environment to prevent moisture uptake, which can affect stability and purity. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.