Description

3-(2-Pyridyl)-L-Alanine is a specialized non-proteinogenic amino acid derivative featuring a pyridyl side chain. This unique structure makes it a valuable chiral building block and a key intermediate in the synthesis of complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, peptide research, and the development of enzyme inhibitors.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of novel drug candidates, particularly for targeted therapies.
• Peptide Modification & Research: Used to incorporate a pyridyl functional group into peptide sequences, altering their binding affinity, stability, or catalytic properties.
• Enzyme Inhibitor Design: Acts as a core structure or precursor for designing inhibitors that target enzymes with specific active site geometries.
• Ligand Synthesis for Catalysis: Employed in the preparation of chiral ligands for asymmetric synthesis and metal-organic frameworks (MOFs).
• Biochemical Research: Utilized in studies of amino acid metabolism, transport, and incorporation into non-ribosomal peptide synthesis.
• Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in related chemical processes.

Basic Information

Product Name	3-(2-Pyridyl)-L-Alanine
CAS No.	37535-51-6
Molecular Formula	C8H10N2O2
Molecular Weight	166.18 g/mol
Synonyms	L-3-(2-Pyridyl)alanine; (S)-2-Amino-3-(pyrid-2-yl)propanoic acid; 2-Pyridyl-L-alanine; (S)-3-(2-Pyridyl)alanine; H-3-(2-Pyridyl)-Ala-OH; 3-(2-Pyridinyl)-L-alanine; L-β-(2-Pyridyl)alanine; 2-Pyridin-2-yl-L-alanine
EINECS	Contact for details

Quality Control

Our 3-(2-Pyridyl)-L-Alanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing purity, specific rotation, and chromatographic data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Specific Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.