Description

L-4-Pyridylalanine is a non-proteinogenic amino acid derivative featuring a pyridyl side chain, serving as a crucial chiral building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of pharmaceuticals and biochemical probes. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, peptide mimetic design, and the synthesis of enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor programs.
• Peptidomimetics & Conformationally Restricted Peptides: Used to incorporate rigid, heteroaromatic structures into peptide backbones to enhance stability, bioavailability, and target specificity.
• Biochemical Research: Serves as a specialized amino acid analog in studying enzyme-substrate interactions, receptor binding, and metabolic pathways.
• Ligand Synthesis for Catalysis: Employed in the preparation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Potential intermediate in the synthesis of advanced crop protection agents with specific biological activity.

Basic Information

Product Name	L-4-Pyridylalanine
CAS No.	37535-49-2
Molecular Formula	C8H10N2O2
Molecular Weight	166.18 g/mol
Synonyms	L-4-Pyridylalanine; (S)-2-Amino-3-(4-pyridyl)propanoic acid; H-4-Pal-OH; 4-Pyridyl-L-alanine; L-β-(4-Pyridyl)alanine; (S)-3-(4-Pyridyl)alanine; 4-Pyridylalanine; L-4-Pyridyl alanine
EINECS	Contact for details

Quality Control

Our L-4-Pyridylalanine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.