Description

4-(Trifluoromethyl)Benzene-1,2-Diol is a high-purity fluorinated catechol derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the unique combination of the electron-withdrawing trifluoromethyl group and the reactive diol functionality, enabling precise molecular modifications. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty materials sectors, where it is used to build complex molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drugs targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group improves biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Polymer & Material Science: Incorporated into monomers for high-performance polymers, such as polycarbonates and epoxy resins, to impart thermal stability, chemical resistance, and unique surface properties.
• Organic Electronic Materials: A valuable starting material in the synthesis of fluorinated organic semiconductors and charge-transport materials for OLEDs and photovoltaic cells.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring novel fluorination chemistry and developing new synthetic methodologies.

Basic Information

Product Name	4-(Trifluoromethyl)Benzene-1,2-Diol
CAS No.	37519-09-8
Molecular Formula	C7H5F3O2
Molecular Weight	178.11 g/mol
Synonyms	3,4-Dihydroxybenzotrifluoride; 4-(Trifluoromethyl)catechol; 3,4-Dihydroxy-α,α,α-trifluorotoluene; 1,2-Dihydroxy-4-(trifluoromethyl)benzene; Benzene-1,2-diol, 4-(trifluoromethyl)-; α,α,α-Trifluoro-3,4-dihydroxytoluene
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethyl)Benzene-1,2-Diol is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with REACH and other relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. Due to potential sensitivity, it is recommended to store under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	108°C - 112°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.