Description

Amikacin CAS NO 37517-28-5 is a semi-synthetic aminoglycoside antibiotic derived from kanamycin A. It is a critical pharmaceutical active ingredient valued for its broad-spectrum bactericidal activity, particularly against Gram-negative bacteria. This compound is essential for manufacturers in the pharmaceutical industry producing injectable antibiotic formulations for the treatment of serious hospital-acquired infections.

Application

• Primary Active Pharmaceutical Ingredient (API) in injectable antibiotic formulations.
• Used in the production of sterile powders for injection to treat severe infections caused by susceptible strains.
• Key component in combination therapies for complex infections in hospital settings.
• Essential raw material for pharmaceutical companies manufacturing generic and branded parenteral drugs.
• Used in veterinary medicine for the treatment of bacterial infections in animals.
• Critical for research and development of new antibiotic formulations and delivery systems.

Basic Information

Product Name	Amikacin
CAS No.	37517-28-5
Molecular Formula	C22H43N5O13
Molecular Weight	585.60 g/mol
Synonyms	Amikacin Sulfate; Amikacine; Biklin; Amikin; BB-K8; N1-(4-Amino-2-hydroxybutyryl)kanamycin A; (2S)-4-Amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxybutanamide
EINECS	253-531-5

Quality Control

Our Amikacin is manufactured under strict quality management systems to ensure it meets the highest standards for pharmaceutical use. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, in compliance with major pharmacopoeial standards such as USP and EP. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and quality assurance for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
pH (1% solution)	9.5 - 11.5
Water Content (KF)	≤ 10.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%
Bacterial Endotoxins	< 0.17 EU/mg
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.