Description

5-(Pyrrolidin-1-Yl)Pyrimidine-2,4(1H,3H)-Dione is a specialized heterocyclic organic compound featuring a pyrimidine-dione core substituted with a pyrrolidine moiety. This molecular structure makes it a valuable key intermediate and building block in advanced organic synthesis, particularly for the development of novel pharmacologically active molecules. It is primarily utilized by pharmaceutical R&D organizations and fine chemical manufacturers engaged in creating new therapeutic agents, agrochemicals, and high-performance materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and antiviral applications.
• Agrochemical Research: Used as a building block for developing new active ingredients in herbicides, fungicides, and plant growth regulators.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, enzyme inhibitors, and tool compounds for biological pathway investigation.
• Material Science: Acts as a monomer or functional additive in the research of advanced polymers and specialty materials with tailored properties.
• Academic & Contract Research: Essential for synthetic chemistry research in universities and CROs (Contract Research Organizations) exploring novel heterocyclic chemistry.

Basic Information

Product Name	5-(Pyrrolidin-1-Yl)Pyrimidine-2,4(1H,3H)-Dione
CAS No.	37454-54-9
Molecular Formula	C8H11N3O2
Molecular Weight	181.19 g/mol
Synonyms	5-(1-Pyrrolidinyl)-2,4(1H,3H)-pyrimidinedione; 5-(Pyrrolidin-1-yl)pyrimidine-2,4-diol; 5-Pyrrolidin-1-yl-1H-pyrimidine-2,4-dione; 2,4-Dihydroxy-5-(pyrrolidin-1-yl)pyrimidine; 5-Pyrrolidino-2,4(1H,3H)-pyrimidinedione; 5-(N-Pyrrolidino)uracil; 37454-54-9 (CAS)
EINECS	Contact for details

Quality Control

Our 5-(Pyrrolidin-1-Yl)Pyrimidine-2,4(1H,3H)-Dione is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet exacting customer specifications. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.