Description

(S)-n-Acetyl-2-Naphthylalanine is a chiral, non-natural amino acid derivative featuring a naphthyl side chain. This compound is a valuable chiral building block and intermediate in advanced organic synthesis, particularly for the development of pharmaceuticals and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide mimetic design, enzyme inhibitor studies, and the synthesis of complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including protease inhibitors and receptor antagonists.
• Peptidomimetics: Used to incorporate a rigid, hydrophobic naphthyl group into peptide backbones to enhance stability, bioavailability, and binding affinity.
• Asymmetric Synthesis: Serves as a starting material or auxiliary in stereoselective chemical reactions to construct complex chiral centers.
• Biochemical Research: Employed in the study of enzyme-substrate interactions and as a standard or reagent in analytical method development.
• Material Science: Potential monomer for the synthesis of specialty polymers with unique optical or structural properties.

Basic Information

Product Name	(S)-n-Acetyl-2-Naphthylalanine
CAS No.	37439-99-9
Molecular Formula	C₁₆H₁₅NO₃
Molecular Weight	269.30 g/mol
Synonyms	(S)-2-Acetamido-3-(naphthalen-2-yl)propanoic acid; N-Acetyl-2-naphthyl-L-alanine; L-N-Acetyl-2-naphthylalanine; (S)-N-Acetyl-2-naphthylalanine; (2S)-2-Acetamido-3-(naphthalen-2-yl)propanoic acid; N-Acetyl-L-2-naphthylalanine; N-Ac-2-Nal-OH
EINECS	Contact for details

Quality Control

Our (S)-n-Acetyl-2-Naphthylalanine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, specific rotation, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Specific Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.