Description

L-Isovaline, Methyl Ester (9Ci) is a high-purity, non-proteinogenic amino acid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a crucial chiral building block and intermediate for the development of novel bioactive molecules and fine chemicals. It is primarily utilized by research institutions, pharmaceutical development labs, and specialty chemical manufacturers engaged in peptide mimetics, medicinal chemistry, and the synthesis of complex natural products.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for neurological and metabolic targets.
• Peptidomimetics & Bioactive Molecule Synthesis: Used to incorporate the unique isovaline structure into peptide analogs and other bioactive compounds to study structure-activity relationships.
• Asymmetric Synthesis: Employed as a chiral auxiliary or building block in stereoselective organic synthesis to construct complex molecular architectures.
• Biochemical Research: Serves as a standard or reagent in metabolic pathway studies and enzyme inhibition assays due to its non-standard amino acid profile.
• Fine Chemical Production: An intermediate in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.

Basic Information

Product Name	L-Isovaline, Methyl Ester (9Ci)
CAS No.	37432-10-3
Molecular Formula	C6H13NO2
Molecular Weight	131.17 g/mol
Synonyms	L-2-Amino-2-methylbutanoic acid methyl ester; Methyl L-isovaline; Methyl (S)-2-amino-2-methylbutanoate; (S)-2-Amino-2-methylbutyric acid methyl ester; L-α-Aminoisovaleric acid methyl ester; Isovaline methyl ester; 37432-10-3
EINECS	Contact for details

Quality Control

Our L-Isovaline, Methyl Ester (9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, identity confirmation by IR and NMR spectroscopy, and impurity profiling. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (L-Isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.