Description

Isodiazepam is a high-purity benzodiazepine derivative of significant interest in pharmaceutical research and development. This compound serves as a crucial intermediate for synthesizing novel active pharmaceutical ingredients (APIs) and for conducting pharmacological studies. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of central nervous system (CNS) therapeutics and analytical reference standards.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced benzodiazepine-based active pharmaceutical ingredients (APIs).
• Research & Development: Used as a reference standard and starting material in medicinal chemistry for developing new therapeutic agents targeting the CNS.
• Analytical Chemistry: Serves as a certified reference material (CRM) for method development, validation, and quality control testing in analytical laboratories.
• Preclinical Studies: Employed in pharmacological and toxicological research to investigate structure-activity relationships (SAR) and metabolic pathways.
• Fine Chemical Synthesis: A versatile intermediate for custom synthesis and the production of specialized, high-value chemical entities.

Basic Information

Product Name	Isodiazepam
CAS No.	37388-25-3
Molecular Formula	C₁₆H₁₃ClN₂O
Molecular Weight	284.74 g/mol
Synonyms	7-Chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one; Desmethyldiazepam; Nordazepam; Nordiazepam; Desoxydemoxepam; A 101
EINECS	Contact for details

Quality Control

Our Isodiazepam is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and related substances, residual solvent analysis, and identity confirmation (IR, MS). A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with in-house specifications tailored for research and pharmaceutical intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.