Description

Erabutoxin C is a potent, short-chain neurotoxic peptide isolated from the venom of the sea snake *Laticauda semifasciata*. This highly specific compound serves as a crucial pharmacological tool for studying nicotinic acetylcholine receptors (nAChRs) due to its competitive antagonistic activity. It is primarily utilized by research institutions and pharmaceutical companies in neuroscience, toxicology, and drug discovery programs. Erabutoxin C CAS NO 37357-76-9 represents a high-purity, well-characterized standard for advanced biochemical research.

Application

• Neuroscience Research: As a selective antagonist for muscle-type and neuronal nicotinic acetylcholine receptors to study receptor function, structure, and signaling pathways.
• Pharmacological Tool Development: Used in the development and validation of high-throughput screening assays for identifying novel nAChR modulators.
• Toxicology Studies: Employed as a reference standard in venom research and for understanding the mechanism of action of snake neurotoxins.
• Structural Biology: Utilized in X-ray crystallography and NMR studies to investigate toxin-receptor interactions at the molecular level.
• Drug Discovery: Serves as a lead compound or template for designing new therapeutic agents targeting cholinergic systems.
• Diagnostic Reagent Manufacturing: Potential use in the development of specialized diagnostic kits for detecting specific neurotoxins or receptor abnormalities.

Basic Information

Product Name	Erabutoxin C
CAS No.	37357-76-9
Molecular Formula	C184H273N51O55S7
Molecular Weight	Approx. 4280.9 g/mol
Synonyms	Erabutoxin C; Laticauda semifasciata toxin C; Sea snake neurotoxin C; Short-chain neurotoxin C; Erabutoxin C (Laticauda semifasciata); Erabutoxin C Peptide; 37357-76-9; Neurotoxin Erabutoxin C
EINECS	Contact for details

Quality Control

Our Erabutoxin C is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high biological activity. Each lot is characterized using advanced analytical techniques including HPLC, mass spectrometry, and amino acid analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and biological activity is provided with every shipment, supporting compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant or under an inert atmosphere. Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (Protein Content)	≥ 90%
Biological Activity	Confirmed by in vitro assay (Contact for details)
Water Content (KF)	≤ 5.0%
Endotoxin Level	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.