Description

Vasoactive Intestinal Peptide CAS NO 37221-79-7 is a 28-amino acid neuroendocrine peptide that functions as a potent vasodilator and smooth muscle relaxant. This compound is of critical importance in biochemical research and pharmaceutical development due to its wide-ranging physiological effects on the cardiovascular, respiratory, and central nervous systems. It is primarily required by research institutions, diagnostic manufacturers, and biopharmaceutical companies engaged in neuroscience, endocrinology, and the development of therapeutic agents for related disorders.

Application

• Biomedical Research: Used as a critical reference standard and active agent in neuroscience and endocrinology studies to investigate its role in neurotransmission, vasodilation, and immune modulation.
• Pharmaceutical Development: Serves as a key starting material or reference compound in the R&D of novel therapeutics targeting conditions like erectile dysfunction, pulmonary hypertension, and neurodegenerative diseases.
• Diagnostic Manufacturing: Employed in the production of immunoassay kits, ELISA tests, and other diagnostic reagents for the quantitative measurement of VIP or related biomarkers in clinical samples.
• Cell Culture & Physiology: Applied in *in vitro* studies to examine its effects on smooth muscle relaxation, ion channel activity, and cellular signaling pathways in various cell lines.
• Academic Research: Utilized in university and institutional labs for fundamental research into gastrointestinal motility, circadian rhythms, and its potential anti-inflammatory properties.

Basic Information

Product Name	Vasoactive Intestinal Peptide
CAS No.	37221-79-7
Molecular Formula	C₁₄₇H₂₃₈N₄₄O₄₂S
Molecular Weight	3325.8 g/mol
Synonyms	VIP; Vasoactive Intestinal Polypeptide; PHM27; VIP, human; VIP (1-28), human; Porcine Intestinal Peptide; 28-L-Vasoactive intestinal peptide; SC-10063
EINECS	Contact for details

Quality Control

Our Vasoactive Intestinal Peptide is produced and tested under stringent quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity determination, mass spectrometry for identity confirmation, and amino acid analysis. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing all relevant specifications to ensure the material meets the exacting standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated under an inert atmosphere. Allow the vial to warm to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Composition	Conforms to theoretical values
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Biological Activity	Assayed (Contact for details)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.