Description

L-Tyrosine, 3-Hydroxy-n-(5-Oxo-L-Prolyl)-, Hydrate (2:3) is a specialized dipeptide derivative of the amino acids L-tyrosine and L-pyroglutamic acid. This compound is valued for its role as a key synthetic intermediate and building block in advanced pharmaceutical and biochemical research. It is primarily required by manufacturers and R&D laboratories in the pharmaceutical, peptide synthesis, and life science sectors for developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate specific tyrosine and pyroglutamate motifs.
• Biochemical Research: Serves as a substrate or reference standard in enzymatic studies and metabolic pathway research.
• Cosmetic Peptides: A potential ingredient in the development of advanced anti-aging and skin-care peptide formulations.
• Neuroscience Research: Investigated for its role in neurotransmitter precursor pathways and related biochemical studies.

Basic Information

Product Name	L-Tyrosine, 3-Hydroxy-n-(5-Oxo-L-Prolyl)-, Hydrate (2:3)
CAS No.	37166-12-4
Molecular Formula	C14H16N2O6 • 1.5H2O
Molecular Weight	331.30 g/mol (Anhydrous basis)
Synonyms	L-Pyroglutamyl-L-tyrosine Hydrate; 5-Oxo-L-prolyl-L-tyrosine Hydrate; L-Pyroglutamyl-L-tyrosine Sesquihydrate; Pyroglutamyltyrosine; pGlu-Tyr; (S)-2-((S)-5-Oxo-2-pyrrolidinecarboxamido)-3-(4-hydroxyphenyl)propanoic Acid Hydrate; NSC 334913; L-Tyrosine, N-(5-oxo-L-prolyl)-, hydrate
EINECS	Contact for details

Quality Control

Our L-Tyrosine, 3-Hydroxy-n-(5-Oxo-L-Prolyl)-, Hydrate (2:3) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade standards suitable for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, water content, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	7.0% - 9.0%
Optical Rotation	Specific range available on COA
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.2%
Related Substances (HPLC)	Individual impurity < 0.5%; Total impurities < 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.