Description

2,4-Dichloropyrimidine-5-Carboxylic Acid is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a building block for creating novel organic electronic materials and ligands for metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	2,4-Dichloropyrimidine-5-Carboxylic Acid
CAS No.	37131-89-8
Molecular Formula	C5H2Cl2N2O2
Molecular Weight	192.99 g/mol
Synonyms	5-Pyrimidinecarboxylic acid, 2,4-dichloro-; 2,4-Dichloro-5-pyrimidinecarboxylic acid; 2,4-Dichloropyrimidine-5-carboxylic acid; 2,4-Dichloro-5-carboxypyrimidine; 2,4-Dichloro-5-pyrimidine carboxylic acid; 2,4-Dichlor-5-pyrimidincarbonsäure (German); Acide 2,4-dichloro-5-pyrimidinecarboxylique (French)
EINECS	Contact for details

Quality Control

Our 2,4-Dichloropyrimidine-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.